CBD Isolation Equipment

Pope's isolation and crystallization equipment is used to produce high-purity CBD isolate

Pope Turnkey CBD Isolation Equipment

When purity is the goal, Pope delivers the complete solution. Our cannabinoid isolation systems are trusted by processors worldwide to produce high-purity CBD isolate—typically 99%+—through a repeatable, efficient crystallization and separation process.

Whether you’re operating at the lab scale or transitioning to full-scale production, Pope offers a full suite of equipment engineered for cannabinoid isolation, including crystallization vessels, filter-dryers, and fully integrated turnkey systems. Backed by decades of chemical processing expertise, our systems help ensure consistency, product quality, and operator safety—every step of the way.

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Turnkey Cannabinoid Isolation Systems

Pope’s turnkey isolation solutions support the full CBD isolate production workflow—from cannabinoid-rich distillate to dry, crystalline isolate. Systems are designed to control temperature, agitation, and filtration conditions to promote effective crystal growth and safe, contained separation from solvent-rich mother liquor.

Systems include:

  • Jacketed crystallization reactors with controlled agitation

  • Nutsche filter-dryers for closed-system filtration and vacuum drying

  • Integrated vacuum, chilling, heating, and control systems

  • Optional solvent recovery for mother liquor reuse

Available sizes:

  • 5L Reactor + 4L Nutsche – Benchtop R&D

  • 30L / 25L, 60L / 50L, 120L / 100L, 200L / 170L, 400L / 350L – Pilot to industrial-scale systems

  • Custom configurations available

These systems are ideal for GMP and non-GMP environments alike, and can be adapted to support in-line decarboxylation, distillation, or recovery steps depending on your process needs.

 

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Nutsche Filter-Dryers

Once crystals are formed, efficient filtration and drying are essential. Pope’s nutsche filter-dryers provide a high-performance, closed-system solution that protects both product and operator while maintaining solvent containment and process cleanliness.

Key benefits:

  • Sealed system to prevent contamination and reduce solvent exposure

  • Vacuum and pressure operation for faster filtration and drying

  • Jacketed stainless steel construction for precise temperature control

  • Agitation features for mixing, washing, and cake discharge

  • Available from 4L to 350L with custom options for larger-scale needs

These filter-dryers are especially effective for high-purity isolate production, improving both safety and final product quality compared to open filtration methods.

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CBD Crystallization Vessels & Reactors

Crystallization is a delicate process that requires precise control over temperature and agitation. Pope offers a range of stainless steel and glass-jacketed vessels and reactors to support this stage of cannabinoid isolation.

Our cbd crystallization reactors are available in a variety of sizes to suit your batch volumes, with features such as:

  • Jacketed construction for integrated heating and cooling

  • Agitation systems with variable speed control

  • Vacuum and pressure capability

  • Clean-in-place (CIP) and drain options for easy maintenance

  • Configurable ports for sensors, sampling, or process connections

Whether you’re conducting small-batch R&D or scaling up crystallization for production, Pope reactors provide the visibility, control, and reliability you need to produce consistent, high-quality isolates.

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Integrated Processing Solutions

Pope’s isolation systems can be combined with our wiped-film stills, decarboxylation reactors, and solvent recovery units to create a fully integrated cannabinoid purification line. Whether you're just starting out or scaling up, Pope delivers the proven tools and support you need to produce high-purity isolates with confidence.